6X85: Crystal Structure of TNFalpha with indolinone compound 9

PDB ID: 6X85Download
MMDB ID: 197433
PDB Deposition Date: 2020/6/1
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 6X85: trimeric; determined by author and by software (PISA)
Molecular Components in 6X85
Label Count Molecule
Proteins (3 molecules)
3
Tumor Necrosis Factor
(Gene symbol: TNF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-{[2-(difluoromethoxy)phenyl]methyl}-2,2-dimethyl-1,2-dihydro-3H-indol-3-one1-{[2-(difluoromethoxy)phenyl]methyl}-2,2-dimethyl-1,2-dihydro-3H-indol-3-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303