6X81: Crystal Structure of TNFalpha with isoquinoline compound 2

PDB ID: 6X81Download
MMDB ID: 197430
PDB Deposition Date: 2020/6/1
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.81  Å
Source Organism:
Similar Structures:
Biological Unit for 6X81: trimeric; determined by author and by software (PISA)
Molecular Components in 6X81
Label Count Molecule
Proteins (3 molecules)
3
Tumor Necrosis Factor
(Gene symbol: TNF)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
[4-(isoquinolin-8-yl)phenyl]acetonitrile[4-(isoquinolin-8-yl)phenyl]acetonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303