6X7A: Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT572

PDB ID: 6X7ADownload
MMDB ID: 202568
PDB Deposition Date: 2020/5/29
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 2.08  Å
Source Organism:
Similar Structures:
Biological Unit for 6X7A: hexameric; determined by author and by software (PISA)
Molecular Components in 6X7A
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (72 molecules)
1
6
4-(4-cyclohexyl-3,4-dihydro-2~{H}-pyridin-1-yl)-1-(4-$l^{2}-fluoranylcyclohexa-1,3,5-trien-1-yl)butan-1-one4-(4-cyclohexyl-3,4-dihydro-2~{H}-pyridin-1-yl)-1-(4-$l^{2}-fluoranylcyclohexa-1,3,5-trien-1-yl)butan-1-one
2
6
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
42
GLYCEROLGLYCEROL
4
12
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303