6X6I: Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT543

PDB ID: 6X6IDownload
MMDB ID: 202565
PDB Deposition Date: 2020/5/28
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.904  Å
Source Organism:
Similar Structures:
Biological Unit for 6X6I: hexameric; determined by author and by software (PISA)
Molecular Components in 6X6I
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (48 molecules)
1
6
4-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one4-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one
2
30
GLYCEROLGLYCEROL
3
6
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303