6X5P: Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors

PDB ID: 6X5PDownload
MMDB ID: 189315
PDB Deposition Date: 2020/5/26
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.997  Å
Source Organism:
Similar Structures:
Biological Unit for 6X5P: dimeric; determined by author and by software (PISA)
Molecular Components in 6X5P
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
3-chloro-4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide3-chloro-4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide
2
4
CITRIC ACIDCITRIC ACID
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303