6X5J: Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors

PDB ID: 6X5JDownload
MMDB ID: 189312
PDB Deposition Date: 2020/5/26
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.513  Å
Source Organism:
Similar Structures:
Biological Unit for 6X5J: dimeric; determined by author and by software (PISA)
Molecular Components in 6X5J
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
1
Coagulation Factor IX
(Gene symbol: F9)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
GLYCEROLGLYCEROL
2
1
2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
3
1
SODIUM IONSODIUM ION
4
4
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303