6X3S: Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with bicuculline methbromide

PDB ID: 6X3SDownload
MMDB ID: 192172
PDB Deposition Date: 2020/5/21
Updated in MMDB: 2020/09
Experimental Method:
electron microscopy
Resolution: 3.12  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6X3S: nonameric; determined by author
Molecular Components in 6X3S
Label Count Molecule
Proteins (9 molecules)
2
Gamma-aminobutyric Acid Receptor Subunit Beta-2
Molecule annotation
2
Gamma-aminobutyric Acid Receptor Subunit Alpha-1
Molecule annotation
1
Gamma-aminobutyric Acid Type a Receptor Subunit Gamma-2
Molecule annotation
2
Kappa FAB Light Chain
Molecule annotation
2
Igg2b FAB Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (23 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
7
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
(5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium(5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303