6X21: Crystal structure of PT1673 bound to HIF2a-B*:ARNT-B* complex

PDB ID: 6X21Download
MMDB ID: 202308
PDB Deposition Date: 2020/5/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.54  Å
Source Organism:
Similar Structures:
Biological Unit for 6X21: dimeric; determined by author and by software (PISA)
Molecular Components in 6X21
Label Count Molecule
Proteins (2 molecules)
1
Endothelial PAS Domain-containing Protein 1
(Gene symbol: EPAS1)
Molecule annotation
1
Aryl Hydrocarbon Receptor Nuclear Translocator
(Gene symbol: ARNT)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(3-bromo-5-fluorophenoxy)-4-[(difluoromethyl)sulfonyl]-2-nitrobenzene1-(3-bromo-5-fluorophenoxy)-4-[(difluoromethyl)sulfonyl]-2-nitrobenzene
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303