6WXN: EGFR(T790M/V948R) in complex with LN3844

PDB ID: 6WXNDownload
MMDB ID: 201987
PDB Deposition Date: 2020/5/11
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.76  Å
Source Organism:
Similar Structures:
Biological Unit for 6WXN: monomeric; determined by author
Molecular Components in 6WXN
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-6-fluoro-3-hydroxybenzamideN-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-6-fluoro-3-hydroxybenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303