6WXJ: CSF1R signaling is a regulator of pathogenesis in progressive MS

PDB ID: 6WXJDownload
MMDB ID: 198530
PDB Deposition Date: 2020/5/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.62  Å
Source Organism:
Similar Structures:
Biological Unit for 6WXJ: monomeric; determined by author and by software (PISA)
Molecular Components in 6WXJ
Label Count Molecule
Protein (1 molecule)
1
Macrophage Colony-stimulating Factor 1 Receptor
(Gene symbol: CSF1R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(3-{[(2S)-2-(6-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine4-(3-{[(2S)-2-(6-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303