6WX3: High resolution Tryptophan Synthase crystal structure from Salmonella typhimurium in complex with F9 inhibitor in the alpha-site, Cesium ion at the metal coordination site and internal aldimine form

PDB ID: 6WX3Download
MMDB ID: 199538
PDB Deposition Date: 2020/5/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6WX3: tetrameric; determined by author and by software (PISA)
Molecular Components in 6WX3
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
Molecule annotation
2
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
2
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
2
2
CHLORIDE IONCHLORIDE ION
3
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
4
4
CESIUM IONCESIUM ION
5
8
BICINEBICINE
6
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303