6WVZ: Crystal structure of anti-MET Fab arm of amivantamab in complex with human MET

PDB ID: 6WVZDownload
MMDB ID: 201336
PDB Deposition Date: 2020/5/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6WVZ: trimeric; determined by author and by software (PISA)
Molecular Components in 6WVZ
Label Count Molecule
Proteins (3 molecules)
1
Heavy Chain of Anti-met FAB of Amivantamab
Molecule annotation
1
Light Chain of Anti-met FAB of Amivantamab
Molecule annotation
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-L-fucopyranosealpha-L-fucopyranose
3
1
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303