6WS5: Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT

PDB ID: 6WS5Download
MMDB ID: 199198
PDB Deposition Date: 2020/4/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.472  Å
Source Organism:
Similar Structures:
Biological Unit for 6WS5: trimeric; determined by author and by software (PISA)
Molecular Components in 6WS5
Label Count Molecule
Proteins (3 molecules)
1
DNA Repair Protein Rev1
(Gene symbol: REV1)
Molecule annotation
1
Mitotic Spindle Assembly Checkpoint Protein Mad2b
(Gene symbol: MAD2L2)
Molecule annotation
1
DNA Polymerase Zeta Catalytic Subunit
(Gene symbol: REV3L)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303