6WRZ: Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove

PDB ID: 6WRZDownload
MMDB ID: 187628
PDB Deposition Date: 2020/4/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6WRZ: dimeric; determined by author and by software (PISA)
Molecular Components in 6WRZ
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATEP1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
3
1
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE7-METHYL-GUANOSINE-5'-TRIPHOSPHATE
4
10
SULFATE IONSULFATE ION
5
4
CHLORIDE IONCHLORIDE ION
6
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303