6WJ2: CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state

PDB ID: 6WJ2Download
MMDB ID: 191927
PDB Deposition Date: 2020/4/11
Updated in MMDB: 2020/09
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6WJ2: octameric; determined by author
Molecular Components in 6WJ2
Label Count Molecule
Proteins (8 molecules)
1
Ragulator Complex Protein Lamtor1
(Gene symbol: LAMTOR1)
Molecule annotation
1
Ragulator Complex Protein Lamtor2
(Gene symbol: LAMTOR2)
Molecule annotation
1
Ragulator Complex Protein Lamtor3
(Gene symbol: LAMTOR3)
Molecule annotation
1
Ragulator Complex Protein Lamtor4
(Gene symbol: LAMTOR4)
Molecule annotation
1
Ragulator Complex Protein Lamtor5
(Gene symbol: LAMTOR5)
Molecule annotation
1
Ras-related Gtp-binding Protein a
(Gene symbol: RRAGA)
Molecule annotation
1
Ras-related Gtp-binding Protein C
(Gene symbol: RRAGC)
Molecule annotation
1
Sodium-coupled Neutral Amino Acid Transporter 9
(Gene symbol: SLC38A9)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
1
9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303