6WIC: Pre-catalytic quaternary complex of human Polymerase Mu on a complementary DNA double-strand break substrate

PDB ID: 6WICDownload
MMDB ID: 193686
PDB Deposition Date: 2020/4/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6WIC: pentameric; determined by author and by software (PISA)
Molecular Components in 6WIC
Label Count Molecule
Protein (1 molecule)
1
DNA-directed Dna/rna Polymerase MU
Molecule annotation
Nucleotides(4 molecules)
1
DNA (5'-d(*cp*gp*gp*cp*ap*t)-3')
Molecule annotation
1
DNA (5'-d(*ap*cp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*gp*tp*a)-3')
Molecule annotation
1
DNA (5'-d(p*gp*cp*cp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
SODIUM IONSODIUM ION
4
1
POTASSIUM IONPOTASSIUM ION
5
1
CHLORIDE IONCHLORIDE ION
6
1
GLYCEROLGLYCEROL
7
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
8
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303