6WI3: Histone deacetylases complex with peptide macrocycles

PDB ID: 6WI3Download
MMDB ID: 201086
PDB Deposition Date: 2020/4/8
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 6WI3: hexameric; determined by author and by software (PISA)
Molecular Components in 6WI3
Label Count Molecule
Proteins (3 molecules)
3
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
FGH
3
(SHA)W(DTH)DN(DSN)(DME)(DAS)K peptide macrocycle
1
3
ZINC IONZINC ION
2
6
SODIUM IONSODIUM ION
3
1
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
4
3
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
5
4
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303