6WFN: Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4a) identified using DNA encoded library technology

PDB ID: 6WFNDownload
MMDB ID: 189562
PDB Deposition Date: 2020/4/3
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.07  Å
Source Organism:
Similar Structures:
Biological Unit for 6WFN: monomeric; determined by author and by software (PISA)
Molecular Components in 6WFN
Label Count Molecule
Protein (1 molecule)
1
N-alpha-acetyltransferase 50
(Gene symbol: NAA50)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ACETYL COENZYME *AACETYL COENZYME *A
2
1
(4S)-1-methyl-N-{(3S,5S)-5-[4-(methylcarbamoyl)-1,3-thiazol-2-yl]-1-[4-(1H-tetrazol-5-yl)benzene-1-carbonyl]pyrrolidin-3-yl}-2,6-dioxohexahydropyrimidine-4-carboxamide(4S)-1-methyl-N-{(3S,5S)-5-[4-(methylcarbamoyl)-1,3-thiazol-2-yl]-1-[4-(1H-tetrazol-5-yl)benzene-1-carbonyl]pyrrolidin-3-yl}-2,6-dioxohexahydropyrimidine-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303