6WAD: Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor

PDB ID: 6WADDownload
MMDB ID: 191925
PDB Deposition Date: 2020/3/25
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 6WAD: dimeric; determined by author and by software (PISA)
Molecular Components in 6WAD
Label Count Molecule
Proteins (2 molecules)
2
Protein Arginine N-methyltransferase 6
(Gene symbol: PRMT6)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
2
5-bromo-N-(diphenylmethyl)-N-methylthiophene-2-carboxamide5-bromo-N-(diphenylmethyl)-N-methylthiophene-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303