6W9G: Crystal Structure of the Fab fragment of humanized 5c8 antibody containing the fluorescent non-canonical amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine in complex with CD40L at pH 6.8

PDB ID: 6W9GDownload
MMDB ID: 196732
PDB Deposition Date: 2020/3/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 6W9G: nonameric; determined by author
Molecular Components in 6W9G
Label Count Molecule
Proteins (9 molecules)
3
Cd40 Ligand
(Gene symbol: CD40LG)
Molecule annotation
3
5c8* FAB (Heavy Chain)
Molecule annotation
3
5c8* FAB (Light Chain)
Molecule annotation
Chemicals and Non-standard biopolymers (53 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
9
alpha-D-mannopyranosealpha-D-mannopyranose
4
8
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
6
21
trimethylamine oxidetrimethylamine oxide
7
3
2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
8
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303