6W8H: H-PGDS complexed with inhibitor 1Y

PDB ID: 6W8HDownload
MMDB ID: 195265
PDB Deposition Date: 2020/3/20
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 6W8H: dimeric; determined by author and by software (PISA)
Molecular Components in 6W8H
Label Count Molecule
Proteins (2 molecules)
2
Hematopoietic Prostaglandin D Synthase
(Gene symbol: HPGDS)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
GLUTATHIONEGLUTATHIONE
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
7-cyclopropyl-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-1,8-naphthyridine-3-carboxamide7-cyclopropyl-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-1,8-naphthyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303