6W5X: Crystal structure of human polymerase eta complexed with N7-benzylguanine and dCTP*

PDB ID: 6W5XDownload
MMDB ID: 199791
PDB Deposition Date: 2020/3/14
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.59  Å
Source Organism:
Similar Structures:
Biological Unit for 6W5X: trimeric; determined by author and by software (PISA)
Molecular Components in 6W5X
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
(Gene symbol: POLH)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*cp*ap*tp*(drg)p*cp*tp*cp*ap*cp*ap*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*ap*gp*tp*gp*tp*gp*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
GLYCEROLGLYCEROL
2
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
3
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303