6W5M: Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02)

PDB ID: 6W5MDownload
MMDB ID: 200277
PDB Deposition Date: 2020/3/13
Updated in MMDB: 2022/10
Experimental Method:
electron microscopy
Resolution: 4.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 6W5M
Label Count Molecule
Proteins (12 molecules)
1
Retinoblastoma-binding Protein 5
Molecule annotation
1
WD Repeat-containing Protein 5
Molecule annotation
1
Histone-lysine N-methyltransferase 2A
Molecule annotation
1
Set1/ash2 Histone Methyltransferase Complex Subunit Ash2
Molecule annotation
2
Histone H3.2
Molecule annotation
2
Histone H4
Molecule annotation
2
Histone H2A Type 1
Molecule annotation
2
Histone H2B 1.1
Molecule annotation
Nucleotides(2 molecules)
1
DNA (147-mer)
Molecule annotation
1
DNA (147-mer)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303