6W4R: Structure of Tdp1 catalytic domain in complex with inhibitor XZ633p

PDB ID: 6W4RDownload
MMDB ID: 199788
PDB Deposition Date: 2020/3/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.819  Å
Source Organism:
Similar Structures:
Biological Unit for 6W4R: monomeric; determined by author and by software (PISA)
Molecular Components in 6W4R
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 1
(Gene symbol: TDP1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
3[N-MORPHOLINO]PROPANE SULFONIC ACID3[N-MORPHOLINO]PROPANE SULFONIC ACID
2
1
4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}benzene-1,2-dicarboxylic acid4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}benzene-1,2-dicarboxylic acid
3
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303