6W44: Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4

PDB ID: 6W44Download
MMDB ID: 201787
PDB Deposition Date: 2020/3/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.64  Å
Source Organism:
Similar Structures:
Biological Unit for 6W44: tetrameric; determined by author and by software (PISA)
Molecular Components in 6W44
Label Count Molecule
Proteins (4 molecules)
4
Hydroxyacid Oxidase 1
(Gene symbol: HAO1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
4
5-[methyl-[(2-propoxypyridin-3-yl)methyl]amino]-2~{H}-indazole-3-carboxylic acid5-[methyl-[(2-propoxypyridin-3-yl)methyl]amino]-2~{H}-indazole-3-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303