6W3A: Structure of unphosphorylated IRE1 in complex with G-7658

PDB ID: 6W3ADownload
MMDB ID: 196131
PDB Deposition Date: 2020/3/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.606  Å
Source Organism:
Similar Structures:
Biological Unit for 6W3A: dimeric; determined by author
Molecular Components in 6W3A
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase/endoribonuclease Ire1
(Gene symbol: ERN1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[6-methyl-5-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide~{N}-[6-methyl-5-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303