6W1Y: Cryo-EM structure of 5HT3A receptor in presence of Palonosetron

PDB ID: 6W1YDownload
MMDB ID: 197412
PDB Deposition Date: 2020/3/4
Updated in MMDB: 2021/01
Experimental Method:
electron microscopy
Resolution: 3.35  Å
Source Organism:
Similar Structures:
Biological Unit for 6W1Y: pentameric; determined by author
Molecular Components in 6W1Y
Label Count Molecule
Proteins (5 molecules)
5
5-hydroxytryptamine Receptor 3A
(Gene symbol: Htr3a)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
30
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranosebeta-D-mannopyranose
3
5
(3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one(3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303