6W0W: Structure of KHK in complex with compound 3

PDB ID: 6W0WDownload
MMDB ID: 193135
PDB Deposition Date: 2020/3/3
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6W0W: dimeric; determined by author and by software (PISA)
Molecular Components in 6W0W
Label Count Molecule
Proteins (2 molecules)
2
Ketohexokinase
(Gene symbol: KHK)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
6-[(3~{R},4~{S})-3,4-bis(oxidanyl)pyrrolidin-1-yl]-2-[(2~{S},3~{R})-2-methyl-3-oxidanyl-azetidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile6-[(3~{R},4~{S})-3,4-bis(oxidanyl)pyrrolidin-1-yl]-2-[(2~{S},3~{R})-2-methyl-3-oxidanyl-azetidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile
2
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303