6VXI: Structure of ABCG2 bound to mitoxantrone

PDB ID: 6VXIDownload
MMDB ID: 187604
PDB Deposition Date: 2020/2/21
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6VXI: dimeric; determined by author
Molecular Components in 6VXI
Label Count Molecule
Proteins (2 molecules)
2
Broad Substrate Specificity Atp-binding Cassette Transporter Abcg2
(Gene symbol: ABCG2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHOLESTEROLCHOLESTEROL
2
1
1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303