6VV8: Mycobacterium tuberculosis dihydrofolate reductase in complex with JEB285

PDB ID: 6VV8Download
MMDB ID: 190135
PDB Deposition Date: 2020/2/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.683  Å
Source Organism:
Similar Structures:
Biological Unit for 6VV8: monomeric; determined by author
Molecular Components in 6VV8
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
COBALT (II) IONCOBALT (II) ION
2
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
1
5-{[3-(1H-indol-3-yl)propanoyl]amino}-1-phenyl-1H-pyrazole-4-carboxylic acid5-{[3-(1H-indol-3-yl)propanoyl]amino}-1-phenyl-1H-pyrazole-4-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303