6VV7: Mycobacterium tuberculosis dihydrofolate reductase in complex with JEB136

PDB ID: 6VV7Download
MMDB ID: 190134
PDB Deposition Date: 2020/2/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.999  Å
Source Organism:
Similar Structures:
Biological Unit for 6VV7: monomeric; determined by author
Molecular Components in 6VV7
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
COBALT (II) IONCOBALT (II) ION
3
1
5-[3-(5-methyl-1H-indol-3-yl)propoxy]-1-phenyl-1H-pyrazole-4-carboxylic acid5-[3-(5-methyl-1H-indol-3-yl)propoxy]-1-phenyl-1H-pyrazole-4-carboxylic acid
4
3
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303