6VV6: Mycobacterium tuberculosis dihydrofolate reductase in complex with JEB113

PDB ID: 6VV6Download
MMDB ID: 190133
PDB Deposition Date: 2020/2/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.235  Å
Source Organism:
Similar Structures:
Biological Unit for 6VV6: monomeric; determined by author
Molecular Components in 6VV6
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: dfrA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
COBALT (II) IONCOBALT (II) ION
2
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
1
1-(4-fluorophenyl)-5-[3-(1H-indol-3-yl)propoxy]-1H-pyrazole-4-carboxylic acid1-(4-fluorophenyl)-5-[3-(1H-indol-3-yl)propoxy]-1H-pyrazole-4-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303