6VV2: Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT1348

PDB ID: 6VV2Download
MMDB ID: 188492
PDB Deposition Date: 2020/2/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6VV2: hexameric; determined by author and by software (PISA)
Molecular Components in 6VV2
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
6
2-{[3-(piperidin-1-yl)propyl]sulfanyl}-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine2-{[3-(piperidin-1-yl)propyl]sulfanyl}-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine
2
6
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
6
GLYCEROLGLYCEROL
4
6
SULFATE IONSULFATE ION
5
6
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
6
SODIUM IONSODIUM ION
7
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303