6VUY: Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT358

PDB ID: 6VUYDownload
MMDB ID: 188488
PDB Deposition Date: 2020/2/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6VUY: hexameric; determined by author and by software (PISA)
Molecular Components in 6VUY
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (78 molecules)
1
6
(7S)-7-phenyl-2-{[3-(piperidin-1-yl)propyl]sulfanyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine(7S)-7-phenyl-2-{[3-(piperidin-1-yl)propyl]sulfanyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine
2
12
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
18
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
12
GLYCEROLGLYCEROL
5
24
SODIUM IONSODIUM ION
6
6
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303