6VUX: Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT388

PDB ID: 6VUXDownload
MMDB ID: 188487
PDB Deposition Date: 2020/2/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 6VUX: hexameric; determined by author and by software (PISA)
Molecular Components in 6VUX
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (54 molecules)
1
6
2-{[(7S)-4-amino-7-ethyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-[2-(piperidin-1-yl)ethyl]acetamide2-{[(7S)-4-amino-7-ethyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-[2-(piperidin-1-yl)ethyl]acetamide
2
24
GLYCEROLGLYCEROL
3
12
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
6
SULFATE IONSULFATE ION
5
6
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303