6VUR: Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT366

PDB ID: 6VURDownload
MMDB ID: 188482
PDB Deposition Date: 2020/2/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6VUR: hexameric; determined by author and by software (PISA)
Molecular Components in 6VUR
Label Count Molecule
Proteins (6 molecules)
6
N-acetyltransferase EIS
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (84 molecules)
1
6
2-({[(3S)-1-methylpiperidin-3-yl]methyl}sulfanyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine2-({[(3S)-1-methylpiperidin-3-yl]methyl}sulfanyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine
2
18
SULFATE IONSULFATE ION
3
18
GLYCEROLGLYCEROL
4
12
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
12
SODIUM IONSODIUM ION
6
18
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303