6VSF: Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-4-oxobutanoic acid(fragment 16)

PDB ID: 6VSFDownload
MMDB ID: 190130
PDB Deposition Date: 2020/2/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.012  Å
Source Organism:
Similar Structures:
Biological Unit for 6VSF: monomeric; determined by author
Molecular Components in 6VSF
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: dfrA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid
2
1
COBALT (II) IONCOBALT (II) ION
3
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
4
1
GLYCEROLGLYCEROL
5
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303