6VSD: Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-((thiophen-2-ylthio)methyl)benzoic acid (fragment 13)

PDB ID: 6VSDDownload
MMDB ID: 190128
PDB Deposition Date: 2020/2/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.693  Å
Source Organism:
Similar Structures:
Biological Unit for 6VSD: monomeric; determined by author
Molecular Components in 6VSD
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: dfrA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
3-(thiophen-2-ylsulfanylmethyl)benzoic acid3-(thiophen-2-ylsulfanylmethyl)benzoic acid
2
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
COBALT (II) IONCOBALT (II) ION
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303