6VS6: Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(furan-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid (fragment 2)

PDB ID: 6VS6Download
MMDB ID: 190125
PDB Deposition Date: 2020/2/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.853  Å
Source Organism:
Similar Structures:
Biological Unit for 6VS6: monomeric; determined by author
Molecular Components in 6VS6
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
COBALT (II) IONCOBALT (II) ION
3
1
3-(furan-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid3-(furan-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid
4
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303