6VRL: Cryo-EM structure of the wild-type human serotonin transporter complexed with I-paroxetine and 8B6 Fab

PDB ID: 6VRLDownload
MMDB ID: 185165
PDB Deposition Date: 2020/2/7
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6VRL: trimeric; determined by author
Molecular Components in 6VRL
Label Count Molecule
Proteins (3 molecules)
1
Sodium-dependent Serotonin Transporter
Molecule annotation
1
8B6 Antibody, Light Chain
Molecule annotation
1
8B6 Antibody, Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
3
1
I-paroxetineI-paroxetine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303