6VPI: TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + D256N + C319V triple mutant disulfide homodimer in complex with AMP-PNP

PDB ID: 6VPIDownload
MMDB ID: 190843
PDB Deposition Date: 2020/2/3
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6VPI: dimeric; determined by author and by software (PISA)
Molecular Components in 6VPI
Label Count Molecule
Proteins (2 molecules)
2
Tpx2 Fragment - Aurora a Kinase Domain Fusion
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
MALONIC ACIDMALONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303