6VPC: Structure of the SpCas9 DNA adenine base editor - ABE8e

PDB ID: 6VPCDownload
MMDB ID: 190631
PDB Deposition Date: 2020/2/3
Updated in MMDB: 2020/08
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6VPC: hexameric; determined by author
Molecular Components in 6VPC
Label Count Molecule
Proteins (3 molecules)
1
Crispr-associated Endonuclease Cas9
Molecule annotation
2
T-rna Adenine Deaminase a V8E (Tada-8e)
Molecule annotation
Nucleotides(3 molecules)
1
Cas9 (Spcas9) Single-guide RNA (Sgrna)
Molecule annotation
1
DNA Target Strand (Ts)
Molecule annotation
1
DNA Non-target Strand (Nts)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303