6VOV: Crystal structure of Syk in complex with GS-9876

PDB ID: 6VOVDownload
MMDB ID: 185159
PDB Deposition Date: 2020/1/31
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6VOV: monomeric; determined by author
Molecular Components in 6VOV
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-(6-aminopyrazin-2-yl)-N-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine6-(6-aminopyrazin-2-yl)-N-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303