6VNH: JAK2 JH1 in complex with PN2-123

PDB ID: 6VNHDownload
MMDB ID: 198748
PDB Deposition Date: 2020/1/29
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6VNH: monomeric; determined by author
Molecular Components in 6VNH
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{5-[(2-{[3,5-difluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-5-methylpyrimidin-4-yl)amino]-2-fluorophenyl}-2-methylpropane-2-sulfonamideN-{5-[(2-{[3,5-difluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-5-methylpyrimidin-4-yl)amino]-2-fluorophenyl}-2-methylpropane-2-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303