6VLT: Crystal Structure of Human P450 2C9*2 Genetic Variant in Complex with Losartan

PDB ID: 6VLTDownload
MMDB ID: 193433
PDB Deposition Date: 2020/1/25
Updated in MMDB: 2020/10
Experimental Method:
x-ray diffraction
Resolution: 3.12  Å
Source Organism:
Similar Structures:
Biological Unit for 6VLT: monomeric; determined by author and by software (PISA)
Molecular Components in 6VLT
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 2C9
(Gene symbol: CYP2C9)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
3
3
5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303