6VKC: Crystal Structure of Inhibitor JNJ-36811054 in Complex with Prefusion RSV F Glycoprotein

PDB ID: 6VKCDownload
MMDB ID: 188044
PDB Deposition Date: 2020/1/20
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6VKC: trimeric; determined by author and by software (PISA)
Molecular Components in 6VKC
Label Count Molecule
Proteins (3 molecules)
3
Prefusion RSV F (Ds-cav1),envelope Glycoprotein
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
alpha-L-fucopyranosealpha-L-fucopyranose
3
3
CHLORIDE IONCHLORIDE ION
4
16
SULFATE IONSULFATE ION
5
1
3-{[5-chloro-1-(4,4,4-trifluorobutyl)-1H-imidazo[4,5-b]pyridin-2-yl]methyl}-1-cyclopropyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one3-{[5-chloro-1-(4,4,4-trifluorobutyl)-1H-imidazo[4,5-b]pyridin-2-yl]methyl}-1-cyclopropyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one
6
3
D(-)-TARTARIC ACIDD(-)-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303