6VIW: BRD4_Bromodomain1 complex with pyrrolopyridone compound 18

PDB ID: 6VIWDownload
MMDB ID: 187300
PDB Deposition Date: 2020/1/14
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.429  Å
Source Organism:
Similar Structures:
Biological Unit for 6VIW: monomeric; determined by author and by software (PISA)
Molecular Components in 6VIW
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303