6VI4: Nanobody-Enabled Monitoring of Kappa Opioid Receptor States

PDB ID: 6VI4Download
MMDB ID: 185454
PDB Deposition Date: 2020/1/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 6VI4: tetrameric; determined by author
Molecular Components in 6VI4
Label Count Molecule
Proteins (4 molecules)
2
Kappa Opioid Receptor
Molecule annotation
2
Nanobody 6
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
(3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide(3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
2
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303