6VGG: Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC

PDB ID: 6VGGDownload
MMDB ID: 195555
PDB Deposition Date: 2020/1/8
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 4.31  Å
Source Organism:
Similar Structures:
Biological Unit for 6VGG: pentameric; determined by author and by software (PISA)
Molecular Components in 6VGG
Label Count Molecule
Proteins (3 molecules)
1
Transcriptional Regulator ERG
(Gene symbol: ERG)
Molecule annotation
1
Runt-related Transcription Factor 2
(Gene symbol: RUNX2)
Molecule annotation
1
Core-binding Factor Subunit Beta
(Gene symbol: CBFB)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*cp*ap*gp*ap*gp*gp*ap*tp*gp*tp*gp*gp*cp*tp*tp*c)-3')
Molecule annotation
1
DNA (5'-d(p*gp*ap*ap*gp*cp*cp*ap*cp*ap*tp*cp*cp*tp*cp*tp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
mithramycinmithramycin
2
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303