6VBN: Crystal Structure of hTDO2 bound to inhibitor GNE1

PDB ID: 6VBNDownload
MMDB ID: 187296
PDB Deposition Date: 2019/12/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.18  Å
Source Organism:
Similar Structures:
Biological Unit for 6VBN: tetrameric; determined by author and by software (PISA)
Molecular Components in 6VBN
Label Count Molecule
Proteins (4 molecules)
4
Tryptophan 2,3-dioxygenase
(Gene symbol: TDO2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
1,5-anhydro-2,3-dideoxy-3-[(5S)-5H-imidazo[5,1-a]isoindol-5-yl]-D-threo-pentitol1,5-anhydro-2,3-dideoxy-3-[(5S)-5H-imidazo[5,1-a]isoindol-5-yl]-D-threo-pentitol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303